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Home > Products > Anti Estrogen Steroids > Pharmaceutical Raw Materials Faslodex Anti Estrogen Steroid Fulvestrant For
 

Pharmaceutical Raw Materials Faslodex Anti Estrogen Steroid Fulvestrant For

Place of Origin:
china
Brand Name:
kafen
Certification:
SGS, UKAS, ISO9001
Model Number:

[email protected]

Min.Order Quantity:
No limit
Price:
negotiate
Packaging Details:
According to your require ments
Delivery Time:
3-5 day
Payment Terms:
T/T, Western Union, MoneyGram
Supply Ability:
5000kg/month
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Product Description

Pharmaceutical Raw Materials Anti Estrogen Steroids Fulvestrant Faslodex For Cutting Cycle

Basic Info.

CAS:129453-61-8
Purity:99%
Appearance:white powder
Synonyms: FASLODEX
Chemical Name:(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
Molecular Fomular:C32H47F5O3S
Molecular Weight:606.77
Density:1.201 g/cm3
Melting Point:104-106℃
Boiling Point:674.8 ℃ at 760 mmHg
Package:10g/foil bag
Usage:To treat estrogen receptor positive metastatic breast cancer in postmenopausal women, with disease progression following antiestrogen therapy.


Fulvestrant Powder Descriptions:

Fulvestrant (Faslodex) is an antagonist of estrogen receptor-α (ERα), a steroid receptor member of the nuclear receptor superfamily of transcription factors, that has been used in the treatment of advanced breast cancer. It is a pure antiestrogen, that is, it has no agonist effects, as distinct from selective estrogen receptor modulators (SERMs) which are capable of context-dependent regulation of the ER.

Fulvestrant injection is used to treat metastatic breast cancer (cancer that has spread) that is hormone-receptor positive in women who have already stopped menstruating (postmenopausal). It is used for women who have breast cancer that has not improved after using other cancer medicines.

Many of the breast cancer tumors will grow when estrogen is available in the body. This medicine blocks the effects of the estrogen hormone in the body. As a result, the amount of estrogen that the tumor is exposed to is reduced, which will limit the growth of the tumor.

Test Item Specification Results
Appearance A white to off-white crystalline powder A white crystalline powder
Identification IR Conform
Any Individual impurity Not more than 0.10% 0.18%
Total impurities Not more than 1.0% 0.44%

Ratio of
isomers

50.0%-60.0%

51.70%

40.0%-50.0%

47.86%
Purity 99.0% 99.56%


Application:

Fulvestrante provided effective second-line therapy in this setting for postmenopausal women who had relapsed or progressed after previous endocrine therapy.

In particular 4 clinical trials in this setting did show similar efficacy to the other hormonal agents (aromatase inhibitors and tamoxifen) with good tolerability profile. Fulvestrante had a lower incidence of joint disorders.

Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive. Drugs that block the effects of these hormones can slow or stop the growth of the breast cancer cells. Fulvestrante stops oestrogen getting to the cancer cells by blocking oestrogen receptors and reducing the number of receptors the cancer cell has.

Fulvestrant Dosage and Storage

Faslodex ( fulvestrant ) is supplied in pre-filled syringes containing 50mg/ml fulvestrant , either as a single 5mL or two 2.5 mL injections . The product must be refrigerated for storage .

High quality with competitive price:

1) Standard: Enterprise Standard
2) All Purity≥98%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out within 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.


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