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CAS 13292-46-1 Rifampin Veterinary Drugs Powder Rifampin for Treating Tuberculos

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Rifampin Veterinary Drugs Powder Rifampin for Treating Tuberculosis CAS:13292-46-1
Product Description:


Product Name: Rifampicin
Synonyms: Rifampin
CAS: 13292-46-1
MF: C43H58N4O12
MW: 822.94
EINECS: 236-312-0
Product Categories: Antibiotics;Organics;Antitubercular;Antibiotics for Research and Experimental Use;Biochemistry;Others (Antibiotics for Research and Experimental Use);Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Peptide Synthesis/Antibiotics;Chiral Reagents;Isotope Labelled Compounds;RIFADIN;antibiotic
Mol File: 13292-46-1.mol



Several semisynthetic derivatives (rifamycin SV, rifampin [rifampicin], rifamide) of natural rifamycins have been used as extended-spectrum antibiotics. Rifamycins interfere with the synthesis of RNA in microorganisms by binding to subunits of sensitive DNA-dependent RNA polymerase. They are active against gram-positive organisms, some mycobacteria, a few strains of gram-negative bacteria (mostly cocci; bacilli are more resistant), some anaerobes, and chlamydiae. At high concentrations, they are also active against several viruses. Fungal and yeast infections resistant to rifampin alone often respond when a rifamycin is added to an antifungal agent (eg, amphotericin B). Resistance to rifamycins may develop rapidly as a 1-step process. For this reason, they should be administered in combination with other antimicrobials, such as penicillins, erythromycin, miconazole, and amphotericin B.


The primary use of the rifamycins in people has been to treat tuberculosis. Rifampin has been used in foals to control Rhodococcus equi pneumonia. Because rifamycins penetrate tissues and cells to a substantial degree, they are particularly effective against intracellular organisms. Rifampin is readily but incompletely (~40%) absorbed from the GI tract, and plasma concentrations peak within 2-4 hr. Concurrent feeding may reduce or delay absorption. Rifampin may also be administered IM or IV.

Approximately 75%-80% of rifampin is bound to plasma proteins. It is widely distributed in body tissues and fluids because of its high lipid solubility. Rifampin is biotransformed to several metabolites, some of which are active, and is primarily excreted in bile (used for cholangitis in people) and to a lesser degree in urine. Enterohepatic cycling of the parent drug and its main metabolite (desacetylrifampin) commonly occurs. The elimination half-life of rifampin is dose dependent: in horses, it is ~6 hr; in dogs, ~8 hr. The plasma half-life progressively shortens by ~40% during the first 2 wk of treatment because of the induction of hepatic microsomal enzymes; conversely, it is increased with hepatic dysfunction.


Rifampin is usually well tolerated and produces few adverse effects. GI disturbances and abnormalities in liver function (icterus) have been reported in people. Hypersensitivity reactions can also result from rifampin administration, and renal failure is a possible consequence when intermittent dosage schedules are followed. Partial, reversible immunosuppression of lymphocytes develops. Urine, feces, saliva, sputum, sweat, and tears are often colored red-orange by rifampinand its metabolites. CNS depression after IV administration and temporary inappetence are seen in horses. The dose range for rifampin in horses is 10-25 mg/kg/day, PO or parenterally.


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(1) High Quality: Kafen Biotech is a steroids manufacturer with its own lab and factory.
The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.
(2) Favorable Price: Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.
(3) Safe Fast Delivery: After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried
(4) Available Shipment Way: EMS,HongKong Post,DHL,TNT,UPS,FedEx,Registered Mail,Air Express,Sea Vessel etc
(5) After-Sale Service: We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you.


Competitive Advantage:
1 High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity≥98%
3) We are manufacturer and can provide high quality products with factory price.
2 Fast and safe delivery:
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2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
3 We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
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Fifth: We arrange the shipment according to your requirements.
Sixth: We offer after-sales service after you receive parcel
Guangzhou Kafen Biotech Co.,Ltd is a renowned pharmaceutical manufacturer, specializing in raw steroid powders in Mainland China. It is not only the leading manufacturer of steroids powder and pharmaceutical raw materials in the central area of China but also exports all over the world. All powders are factory directly supplying.

Our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries. Monthly output is over 100kgs. We cherish a great number of loyal customers serving in gym fields, athletes fields , medical institution ,clinics and so on Top quality products with the most competitive rate .Free samples are available. Flexible and Untraceable payment terms. Exclusive customer service and 24/7 online timely and helpful After-sale service.



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