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Home > Products > Legal Anabolic Steroids > Immune Suppressant Tacrolimus Molecular Formula C44H69NO12 CAS 104987-11-3
 

Immune Suppressant Tacrolimus Molecular Formula C44H69NO12 CAS 104987-11-3

  • Immune Suppressant Tacrolimus Molecular Formula C44H69NO12 CAS 104987-11-3
Place of Origin:
China
Brand Name:
KAFEN
Certification:
SGS, UKAS, ISO9001
Model Number:

104987-11-3

Min.Order Quantity:
No limit
Price:
k.herman@kafenbio.com
Packaging Details:
According to every customerss requirements
Delivery Time:
3-5 day
Payment Terms:
T/T, Western Union, MoneyGram, Bitcoin
Supply Ability:
5000kg / month
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Product Description

Immune Suppressant Tacrolimus Molecular Formula C44H69NO12 CAS 104987-11-3

 


Basic info:

 

Tacrolimus
Purity: 99%
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Melting Point: 113-115° C
Boiling Point: 871.7 ° C at 760 mmHg
Appearance: White powder
Lead time: 1-2 days upon receipt of payment
Delivery time: Usually 4-6 working days by air
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.

 


Application:

 

L Immunosuppression following transplantation It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.

 


Interactions :

 

Also like cyclosporin it has a wide range of interactions, including that with grapefruit which increases plasma-tacrolimus concentration. Several of the newer class of antifungals, especially of the azole class (fluconazole, posaconazole) also increase drug levels by competing for degradative enzymes.

 


Ulcerative colitis:

 

In recent years, tacrolimus has been used to suppress the inflammation associated with ulcerative colitis, a form of inflammatory bowel disease. Although almost exclusively used in trial cases only, tacrolimus has shown to be significantly effective in the suppression of outbreaks of UC.

 


Dermatological Use:

 

As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side-effects.

 

It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids[citation needed]. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.

 

 

TACROLIMUS Specifications:

 

Test

 

Specification

 

Result

 

Description

 

A white crystalline powder

 

Complies

 

Solubility

 

Soluble in Methanol, Ethyl acetate and Chloroform

 

Complies

 

Water

 

≤3.0% 1.3%

Residue on ignition

 

≤0.10%

Complies

 

Heavy metals

 

<10ppm

Complies

 

Isomer

 

≤5.0% 0.56%

Individual Impurity

 

≤0.5% 0.33%

T otalimpurities

 

≤2.0% 0.43%

Assay ( on dry basis

including isomers)

 

≥98.0% 99.8%

Conclusion

The product conforms to the Enterprise specification.

 

 

 

 

Delivery and Packaging :

We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.

 


Competitive Advantage:

1. Rich experience.
Having been specialized in this field for years, we have rich experience and widespread sales network around the word. Our steroid and hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. We are not got good feedback from our guest, but also established long business relationship with them.

2. Great quality and high purity.
Good quality is one secret for our success. All of our products enjoys high purity. Thus, it can make sure our clients need. Welcome order the samples, MOQ just 10 grams.

3. Safest and fastest delivery.
We have mass stock, so that we can arrange the delivery within 24hours once receiving the payment. Tracking number would be informed quickly after shipment. We have our own way of packing which could ship 0.01 kilo to 50 kilo products a time.

4. Good after-sales service.
24/7 is available. We will tell you the package updated info ASAP. And try our best to solve various problems customers encountered!

5. Experiential shopping
Besides raw steroid powder and liquid, we offer hormone solution and formula. We can teach you how to make hormone solution on the site. Any visit to our lab is welcomed.



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