Product name:2,4-Dinitrophenol / DNP
CAS : 51-28-5
Appearance: Buff monoclinic crystal. Soluble in hot water, ethanol, acetone, benzene, chloroform and pyridine insoluble in cold water. Can with water vapor volatilization, heated sublimation.
DNP belongs to a small class of compounds that in many ways, while not 100% accurate can be labeled as manufactured toxins.
Its mode of action, while strong is relatively simple by which the substance uncouples oxidative phosphorylation thereby increasing both body temperature and overall metabolic rate.So how does this work exactly?
By its very nature DNP readily and rapidly destroys ATP, in-fact it thrives and fuels off of it and literally drains your muscle stores of all ATP.By this action the mitochondria are necessarily required to create more ATP to meet desired function or perhaps in most simplistic terms convert food into ATP.
To understand the benefits of DNP we really only need to say two words, "Fat Loss" beyond that there is no other benefit to this synthetic chemical.When you examine many of the other profiles here youll find that most all anabolic steroids have a multitude of purposes as well as several of the non-steroidal compounds such as SERMs, AIs and Peptides, as well as many secondary functions;That simply isn the case with DNP.When it comes to DNP we are not talking about an anabolic steroid, it is often talked about in conjunction, as both are generally and necessarily used at the same time but a steroid it is not.When we talk about DNP the truth is very simple, wee talking about fat loss plain and simple but when steroids are added we are assuredly talking about pure fat loss and not simple body weight loss.
DNP, its role is to make the de-coupling of oxidation and phosphorylation. Once given to 10-4M concentration of mitochondria, the uncoupling effect occurs, oxygen absorption is increased, P: O decline, if further given the high concentration will hinder the absorption of oxygen.
DNP as a mechanism of action uncoupler is: DNP did not inhibit transfer of electrons, but it can eliminate the proton driving force required for the synthesis of ATP.
Since DNP is a lipophilic compound is weakly acidic, it passes through the neutral state proton mitochondrial inner membrane lipid bilayer. When there is a proton gradient across the membrane, it is incorporated in the acidic side of the membrane proton to become a neutral state uncharged, by diffusion through the membrane, and in the alkaline side of the membrane to release a proton, thereby neutralized cross membrane proton gradient.
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