CAS No.: 104987-11-3
Density: 1.19 g/cm3
Melting Point: 113-115° C
Boiling Point: 871.7 ° C at 760 mmHg
Vapour: 1.73E-35mmHg at 25° C
Refractive Index: 1.549
Flash Point: 481 ° C
Appearance: White or off-white crystalline powder
Grade: Pharmaceutical Grade
Lead time: 1-2 days upon receipt of payment
Delivery time: Usually 4-6 working days by air
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
heart liver kidney and bone marrow transplant patients preferred immune-suppressing drugs after the transplant rejection resistant to conventional immunosuppressive regimen, is also the choice of the drug... Adverse reactions similar to cyclosporine. autoimmune eye disease and other autoimmune diseases also play an active role.
It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.
||A white or off-white crystalline powder
||1. IR (USP <197K>)
||2. HPLC retention times
(USP <921> Method I)
|1.6 ~ 3.0%
|Residue on ignition
(USP <231> II)
|£ 20 ppm
||< 20 ppm
|Related substances (In-house HPLC method)
||Ascomycin £ 0.8%
|Acetone £ 2000 ppm
|Assay (on anhydrous basis)
||98.0% ~ 102.0%
|Conclusion: Complied with In-House standard
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Store in cool and dry area and keep away from direct sunlight.oC
2 years, keep in formal storage condition.
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Tacrolimus Powder Legal Anabolic Steroids CAS 104987-11-3 For Immune Suppressant Images