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Home > Products > Local Anesthetic Drugs > CAS 51-05-8 Local Anesthetic Drugs Procaine Hydrochloride Raw Powder
 

CAS 51-05-8 Local Anesthetic Drugs Procaine Hydrochloride Raw Powder

  • CAS 51-05-8 Local Anesthetic Drugs Procaine Hydrochloride Raw Powder
Place of Origin:
China
Brand Name:
Kafen
Certification:
GMP
Model Number:

51-05-8

Min.Order Quantity:
10g
Price:
Negotiable
Packaging Details:
Discreet and disguised
Delivery Time:
Within 24 hours after receiving your payment
Payment Terms:
Western Union, MoneyGram,Bitcoin and Bank Transfer
Supply Ability:
5000KG/Month
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Product Description

Quick Details :

Procaine
Alias : Procaine hydrochloride , 2-(Diethylamino)ethyl 4-aminobenzoate hydrochloride
CAS NO. : 51-05-8
EINECS : 200-077-2
MF : C13H21ClN2O2
MW : 272.77
Melting Point :154-158ºC
Assay : 99%
Appearance : White crystalline powder
Grade : Pharmaceutical Grade
Storage: Shading, Closed preservation
Usage : It is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Description:

Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as . It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.The routes of administration and concentrations are: for local infiltration use 0.25% to 0.5% (via dilution) and for peripheral nerve blocks use 0.5% (via dilution), 1%, and 2%.

Application:

A 1% procaine injection has been recommended for the treatment of extravasation complications associated with venipuncture (along with moist heat, ASA, steroids, antibiotics). It has likewise been recommended for treatment of inadvertent intra-arterial injections (10 ml of 1% procaine), as it helps relieve pain and vascular spasm. Prior to the discovery of Stovaine and , was the most commonly used local anesthetic. Einhorn wished his new discovery to be used for amputations, but surgeons preferred general anesthetic. Dentists, however, found it very useful.

COA:

Product name Procaine HCl  

Appearance

White crystalline powder
Conform

Assay (C13H20N2O2·HCl)

99.0% to 101.0%

99.5%

Melting point

153~158ºC

156.5~157.0ºC

Heavy metals

≤20ppm

<5ppm

Acidity

≤0.02N NaOH 0.5ml

0.3ml

Chromatographic purity

Secondary
spots≤0.5%,sum≤1.0%

Conforms

Loss on drying

≤1.0%

0.06%

Residue on ignition

≤0.15%

0.03%

Bacterial endotoxins

≤0.6EU/mg

<0.6EU/mg

 

 

Procaine HCl Side Effects


Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions.

Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.

Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed.

Procaine may also induce weakening of the myocardium leading to cardiac arrest.

 

 


CAS 51-05-8 Local Anesthetic Drugs Procaine Hydrochloride Raw Powder Images

 

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