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Home > Products > Local Anesthetic Drugs > USP Standard Drug Tetracaine Base Raw Powder Used Local Pain Killer Drug CAS 94
 

USP Standard Drug Tetracaine Base Raw Powder Used Local Pain Killer Drug CAS 94

  • USP Standard Drug Tetracaine Base Raw Powder Used Local Pain Killer Drug CAS 94
Place of Origin:
China
Brand Name:
Kafen
Certification:
GMP
Model Number:

94-24-6

Min.Order Quantity:
10g
Price:
Negotiable
Packaging Details:
Discreet and disguised
Delivery Time:
Within 24 hours after receiving your payment
Payment Terms:
Western Union, MoneyGram,Bitcoin and Bank Transfer
Supply Ability:
5000KG/Month
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Product Description

Product Name Tetracaine
Alias Amethocaine; Pontocaine; Dicaine; Laudocaine
CAS Registry Number 94-24-6
Einecs No 202-316-6
Molecular Formula C15H24N2O2
Molecular Weight 264.36
Purity 99%
Grade Pharmaceutical Grade
Appearance white crytalline powder

 

Description:

 

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group.It is mainly used topically in ophthalmology and as an antipruritic,and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations,tetracaine causes an initial inhibition of spontaneous calcium release events,while at high concentrations, tetracaine blocks release completely.

Tetracaine hydrochloride is indicated for the production of spinal anesthesia for procedures requiring two to three hours. Parenteral administration of Tetracaine hydrochloride stabilizes the neuronal membrane and prevents initiation and transmission of nerve impulses thereby effecting local anesthesia.The onset of action is rapid, and the duration is prolonged (up to two or three hours or longer of surgical anesthesia).Tetracaine hydrochloride is detoxified by plasma esterases to aminobenzoic acid and diethylaminoethanol.

 

Application:

Before using Tetracaine, barbiturates should be taken first. A small amount of adrenaline should be added into Anesthetic to improve capillary contraction, and decrease drug absorption.

You should make a trial before using topical anesthetic. Only without allergic reaction can appropriate amount be used.

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
use:Used for mucosal epidermal anesthesia, nerve tissue anesthesia, epidural anesthesia and Subarachnoid space anesthesia.

In the manufacture of pharmaceutical preparation for external use, to relieve the pain of drugs or medication lesions pain.

 

Tetracaine HCL is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear,nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

 

 COA

Test Items Specification Test Results
Appearance Fine, white, crystalline, odorless powder confirm
Identification ABC in Pass confirm
Solubility Very soluble in water, soluble in Alcohol;
insoluble in Ether and Benzene
confirm
USP Reference standards USP Tetracaine Hydrochloride RS
USP Endotoxin RS.
confirm
Melting point 145~150 degree 146.0~147.5 degree
Chromatographic purity In Pass confirm
Related substance Not more than the reference solution 0.05% confirm
Heavy metals ≤10ppm confirm
PH 4.5-6.5 5.8
Residue on ignition ≤0.10% 0.05%
Loss on Drying ≤ 0.5% 0.19%
Assay 98.0 -101.0% 100.1%


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17 Tetracaine 94-24-6

 


USP Standard Drug Tetracaine Base Raw Powder Used Local Pain Killer Drug CAS 94 Images

 

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