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Home > Products > Muscle Building Steroids > BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647
 

BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647

  • BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647
Place of Origin:
Guangdong
Brand Name:
Kafen
Certification:
USP, GMP ,ISO9001, UKAS,BP
Model Number:

13647-35-3

Min.Order Quantity:
10g
Price:
negotiable
Packaging Details:
Disguised and discreet or according to every customers requirements
Delivery Time:
within 8 hours after receiving your payment
Payment Terms:
D/A, L/C, D/P, T/T, Western Union, MoneyGram, Bitcoin
Supply Ability:
5000kg/month
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Product Description

 

BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome


1. Quick Details:


Product Name:Trilostane
Synonym: Vetoryl
CAS :13647-35-3
Molecular Formula:C20H27NO3
Molecular Weight:329.4333
Assay :99%
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Appearance: White crystalline powder
Usage : Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.

 

 

 

2 . Description:

 

Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushings syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.

Trilostane A drug that interferes with the natural synthesis of steroids and is used to treat breast cancer in post-menopausal women. A brand name is Modrenal.

A short-acting adrenocortical suppressant for oral use in dogs. Trilostane blocks the adrenal gland from making too many steroids. Although steroids are important for various functions of the body, too much can cause problems.

 

 

 

3 . Function:

 

Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.

Trilostane is used in the treatment of Cushings syndrome. It is normally used in short-term treatment until permanent therapy is possible.

Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushings syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.

 

Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5, 4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.

 

 

4 .  COA : 

 

Test Items Specification Results
Identification Positive Confirm
Melting point 257°C to 270°C 261°C -266°C
Appearance White to pale white solid White solid
Heavy metals No more than 20ppm 10ppm
Loss on drying Not more than 0.5% 0.18%
Residue on Ignition Not more than 0.1% 0.02%

Solubility

 

 

 

soluble in dimethyl sulfoxide Conforms
soluble in pyridine Conforms
slightly soluble in ethanol Conforms
slightly soluble in water Conforms
Assay (microbial) Not less than 99.0% 99.5%
Specific Rotation +137-139° 137.0°
Related impurities not more than 1.0% 0.35%
HPLC purity not less than 99.0% 99.6%
Solvent Residues Ethanol<5000ppm 1000ppm
Conclusion Conforms with In-house standard.

 

 


BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647 Images

 

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