Product Description

 

Anxiety Depression Pharmaceutical Azaperone For Pharmaceutical Sedative CAS:1649-18-9

 

Basic Information:

 

Product Name: Azaperone

Synonyms: AZAPERON;AZAPERONE;1-(4-FLUOROPHENYL)-4-[4-(2-PYRIDINYL)-1-PIPERAZINYL]-1-BUTANONE;1-(4-FLUORO-PHENYL)-4-(4-PYRIDIN-2-YL-PIPERAZIN-1-YL)-BUTAN-1-ONE;1-(3-(4-Fluorobenzoyl)propyl)-4-(2-pyridyl)piperazin;1-(4-fluorophenyl)-4-(4-(2-pyridinyl)-1-piperazinyl)-1-butanon;1-Butanone, 1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-;4-fluoro-4-(4-(2-pyridyl)-1-piperazinyl)-butyrophenon

CAS: 1649-18-9

MF: C19H22FN3O

MW: 327.4

EINECS: 216-715-8

Chemical Properties Off-White Solid

Usage H1 antihistamine (nonsedating); leucotriene synthesis blocker

Usage Sedative; tranquilizer.

purity: 99%

 

CERTIFICATE OF ANALYSIS:

 

Product name	Azaperone
CAS No.	1649-18-9	Outer Packing		1KG/BAG
Production date	20170525	Shelf life		20190524
Standard adopted	BP 2010
Items of analysis	Specification		Results
Appearance	White or almost white powder		Meet the Requirements
Solubility	Practically insoluble in water, freely soluble in Acetone and Methylene Chloride, soluble in Alcohol		Confirms
Identification	IR		Positive
Loss on drying	≤0.5%		0.26%
Impurity A	≤0.25%		0.11%
Total impurity B and C	≤0.75%		0.14%
Total impurity	≤1.0%		0.40%
Disregard Limit	≤0.05%		0.05%
Appearance of solution	Clear solution		Confirms
Sulphated ash	≤0.1%		0.08%
Assay:(HPLC)	99-101%		99.8%
Conclusion	Qualified

 

Description:

 

Azaperone is a pyridinylpiperazin and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. It is uncommonly used in humans as an antipsychotic drug.

 

Azaperone acts primarily as a dopamine antagonist but also has some antihistaminic and anticholinergic properties as seen with similar drugs such as haloperidol. Azaperone may cause hypotension and while it has minimal effects on respiration in pigs, high doses in humans can cause respiratory depression.

 

What is Azaperone?

 

Azaperone is really a pyridinylpiperazin and butyrophenone neuroleptic drug with sedative and antiemetic effects, utilized mainly as being a tranquilizer in veterinary medicine. It can be uncommonly used in humans being an antipsychotic drug.

 

Azaperone for Bigs

The most typical use for azaperone is in relatively small doses to reduce aggression in farmed pigs, to stop them fighting as well as to encourage sows to accept piglets. Higher doses can be used anesthesia together with other drugs such as xylazine, tiletamine and zolazepam.

 

Azaperone for giant animals.

Azaperone is also used in in conjunction with strong narcotics like etorphine-or-carfentanil for tranquilizing large animals including elephants. Utilization in horses is avoided as side effects may occur.

 

Application:

 

The most common use for azaperone is in relatively small doses to reduce aggression in farmed pigs, either to stop them fighting or to encourage sows to accept piglets. Higher doses are used for anesthesia in combination with other drugs such as xylazine, tiletamine and zolazepam. Azaperone is also used in combination with strong narcotics such as etorphine or carfentanil for tranquilizing large animals such as elephants. Use in horses is avoided as adverse reactions may occur.

 

Veterinary use

The most common use for azaperone is in relatively small doses to reduce aggression in farmed pigs, either to stop them fighting or to encourage sows to accept piglets. Higher doses are used for anesthesia in combination with other drugs such as xylazine, tiletamine and zolazepam. Azaperone is also used in combination with strong narcotics such as etorphine or carfentanil for tranquilizing large animals such as elephants. Use in horses is avoided as adverse reactions may occur.

 

The European Medicines Agency has established a maximum residue limit for azaperone when administered to pigs.

 

Azaperone (under the brand name Stresnil) was approved for use in pigs in the USA in 1983, under NADA 115-732.

 

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Anxiety Depression Nootropics Pharmaceutical Azaperone For Pharmaceutical Images