Product Name: Unifiram
CAS No. CAS: 272786-64-8
English synonym: UnifiraM;2-[(4-Fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one;(8aR)-2-[(4-fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one;Pyrrolo[1,2-a]pyrazin-6(2H)-one, 2-[(4-fluorophenyl)sulfonyl]hexahydro-
Grade: Pharmaceutical Grade
Molecular Formula: C13H15FN2O3S
Molecular Weight: 298.3332032
Physical State: White Powder
Extended Products: Tablets, Capsules
Usage: For the treatment of Alzheimers dementia, cognitive disorders, nervous system drugs, senile dementia, acetylcholine release agents
Unifiram (DM-232) is another recent entrant in the Racetam family (think piracetam) which is structurally similar to an ampakine and is closely related to Sunifiram (DM-235), with the first studies on the drug being published in 2003. More studies need to be conducted to fully elucidate the effects of Unifiram, but it appears to be effective as a Nootropic and as an anti-amnesic.
Unifiram is a highly potent AMPAkine-like nootropic with antiamnesic and cognition-enhancing effects in animal studies at up to three orders of magnitude higher potency than piracetam.
User reviews and Sunifiram logs point to the fact that this supplement makes information recall much easier and helps you think more clearly. Sunifiram is being compared to Noopept quite a bit because of their similar potency levels. Initial observations suggest that Sunifiram is better as a memory booster while Noopept might have an edge on increasing focus and alertness.
In the few studies done, the most common dose was .1mg/kg in both mice and rats and was found to be anti-amnesic in the water maze test [1,6]; this dose works out to roughly 2mg in an adult human (70kgs). One study also used 1mg/kg in rats and found it to have anti-amnesic effects in rats; this dose would be ~17mg for a healthy adult human (70kgs) .
In the studies conducted, Unifiram was noted to have three primary benefits: anti-amnesia, acetylcholine agonism, and anti-sedative and anti-hypnotic effects. Two of the studies on Unifiram and its analogs focused on its ability to reverse the amnesic effects of AMPA antagonists and its precognitive effects utilizing the Mouse Passive Avoidance test for their experimental methodology. Another study noted that Unifiram appears to increase acetylcholine release in rats; acetylcholine is very strongly correlated to memory and learning. There was one other study done that found, on top of being an anti-amnesic, Unifiram reduces the effects of barbiturates especially the effects of hypnosis and sedation.
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Medical Grade Raw Material Powder , Nootropic Unifiram Steroids CAS 272786-64-8 Images