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Home > Products > Prohormone Steroids > Tacrolimus Raw White Powder Prohormone Steroids For Anti Inflammatory 104987-11
 

Tacrolimus Raw White Powder Prohormone Steroids For Anti Inflammatory 104987-11

Place of Origin:
china
Brand Name:
kafen
Certification:
SGS, UKAS, ISO9001
Model Number:

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No limit
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negotiate
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According to your require ments
Delivery Time:
3-5 day
Payment Terms:
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Supply Ability:
5000kg/month
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Product Description

 

Prohormones Steroids Tacrolimus Raw White Powder For Anti Inflammatory 104987-11-3

 

 

 

Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, Protopic) is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the bodys learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimuras disease, and the skin condition vitiligo.

 

 


Quick Details:


Tacrolimus
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Product Categories:Pharmaceuticals;Chiral Reagents;Fujimycin, Prograf;antibiotic
Chemical Properties: White Crystalline Solid
Assay:99%
Usage: An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.

 

 


Tacrolimus Description:

 

Tacrolimus is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the bodys learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimuras disease, and the skin condition vitiligo.

 

 


Tacrolimus Application:

 

Heart liver kidney and bone marrow transplant patients preferred immune-suppressing drugs after the transplant rejection resistant to conventional immunosuppressive regimen, is also the choice of the drug... Adverse reactions similar to cyclosporine. autoimmune eye disease and other autoimmune diseases also play an active role.

 

 


Tacrolimus Function:

 

It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.

 

It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.

 
 

 

High quality with competitive price:

 

1) Standard: Enterprise Standard
2) All Purity≥98%
3) We are manufacturer and can provide high quality products with factory price.
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3, We have clients throughout the world.
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2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

 

 

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