White Powder Prohormones Steroids Abiraterone For Anti-Cancer 154229-18-2
Alias : 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol
Molecular Formula: C24H31NO
Molecular Weight: 349.51
Appearance: White powder
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Usage: It is indicated for use in combination with prednisone as a treatment for metastatic castration-resistant prostate cancer.
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Storage: Shading, confined preservation
Keeping:Keep at room temperature between 20-25°C out from ligh.
Abiraterone is a new type of hormone therapy. It is also called abiraterone acetate. It is used to treat prostate cancer that has spread to other parts of the body. It may help some men to live longer. It can also help control symptoms. Clinical trials are also using abiraterone for earlier stages of prostate cancer and advanced breast cancer. Abiraterone is associated with a not uncommon rate of serum enzyme elevation during therapy, but has not been clearly linked to cases of clinically apparent liver injury with jaundice.
Abiraterone is a steroidal compound with antiandrogen activity. it is a Cytochrome P450 17A1 Inhibitor. The mechanism of action of abiraterone is as a Cytochrome P450 17A1 Inhibitor, and Cytochrome P450 2D6 Inhibitor, and Cytochrome P450 2C8 Inhibitor that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.
Abiraterone, a steroidal cytochrome P 450 17alpha-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent pr ostate cancer.
Currently, for patients of advanced prostate cancer, androgen deprivation therapy and surgery is generally the preferred method of including drug and surgery in order to reduce the testicular androgen synthesis. However, this treatment can suppress other parts of the body for yielding the male hormone.
Abiraterone is a therapeutic agent for prostate cancer with the English name for Abiraterone. It is developed by researchers coming from the British Royal Marsden Hospital located in southwest (world-renowned cancer research treatment center). It is kind of drug which is able to repress any part of the body for androgen production. It can not only reduce the levels of the prostate-specific antigen (PSA) which represents the tumor activity, but also helps to shrink the tumor. It can also apply to cancer patients who have been subject to chemotherapy in the past, revealing treatment hope.
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