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Home > Products > Sex Enhancement Drugs > Male Sex Enhancement Medicine Epimedium Extract Powder Plant Icariin CAS 489-32

Male Sex Enhancement Medicine Epimedium Extract Powder Plant Icariin CAS 489-32

  • Male Sex Enhancement Medicine Epimedium Extract Powder Plant Icariin CAS 489-32
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Product Description

Basic Info:

Product name Icariin
Synonyms Horny goat weed extract ; ICARIINE ; ICARRIN;epimedium extract ; Epimedium herb Ext ; Epimedium P.E ; Epimedium Brevicornum P.E ; Epimedim Brevicormum P.E
CAS 489-32-7
MF C33H40O15
MW 676.66
Chemical Properties Light yellow to yellow solid
Usage Male Sexual Enhancement

Product Description:

Sex Steroid HormonesIcariin is a chemical compound classified as a flavonol glycoside , a type of flavonoid . It is the 8-prenyl derivative of kaempferol 3,7-O-diglucoside . The compound has been isolated from several species of plants belonging to the genus Epimedium which are commonly known as Horny Goat Weed or Yin Yang Huo . Extracts from these plants are reputed to produce aphrodisiac effects , and are used in traditional Chinese medicine to enhance erectile function .
Sex Steroid Hormones , It is thought that icariin is an active component of Epimedium extracts , as it has been shown to share several mechanisms of action with compounds used in Western medicine to treat impotence . In particular , icariin is a weak PDE5 inhibitor in vitro and enhances the production of nitric oxide , as well as mimicking the effects of testosterone in rats . It is a weak antioxidant and has antidepressant-like effects in mice . It also has neuroprotective effects in rats.


Exterior Light yellow to yellow solid conform
Degree of fineness 100 mesh conform
Loss on drying <5% 3.5%
Residue on ignition <2.5% 2.1%
Icariin >10%(HPLC) 12.9%(HPLC)
Distinguish (+) (+)
Heavy Metal <5PPM conform
bacterial <1000cfu/g 40cfu/g
Mold <100cfu/g <10cfu/g
E. coli Negative Negative
salmonella Negative Negative
Storage conditions Top dry and low temperature sealing Top dry and low temperature sealing
Conclusion conform

To effectively treat bone diseases using bone regenerative medicine , there is an urgent need to develop safe cheap drugs that can potently induce bone formation . Here , we demonstrate the osteogenic effect of icariin , the main active compound of Epimedium pubescens . Icariin induced osteogenic differentiation in pre-osteoblastic MC3T3-E1 cells and mouse primary osteoblasts . Icariin upregulated the mRNA expression levels of the osteoblast marker genes runt-related transcription factor 2 (Runx2) and inhibitor of DNA-binding 1 (Id-1) . The osteogenic effect was inhibited by the introduction of Smad6 or dominant-negative Runx2 , as well as Noggin treatment . Furthermore , icariin induced the mRNA expression of bone morphogenetic protein (BMP)-4 . These data suggest that icariin exerts its potent osteogenic effect through induction of Runx2 expression , production of BMP-4 and activation of BMP signaling . The extremely low cost of icariin and its high abundance make it appealing for bone regenerative medicine .

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