CAS No: 129938-20-1
MF: C21H23NO. HCl
Appearance: White powder, odorless, slightly sweet, soluble in water and alcohol
, marketed as Priligy (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18-64 years old. works by inhibiting the serotonin transporter, increasing serotonins action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, was initially created as an antidepressant. However, unlike other SSRIs, is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant
Treat male premature ejaculation and erectile dysfunction.
Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldingers meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when is used.
However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. , on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drugs accumulation in the body, and therefore reducing side effects.
|2.||Sildenafil Citrate / Sildenafil / Viagra|
|3.||Sildenafil Mesylate / Win 55,212-2 Mesylate|
|4.||Tadalafil / Cialis|
|6.||Vardenafil HCL / Levitra|
|10.||Jin Yang Base|
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