Product Description

Vardenafil Info:

Product Name:Vardenafil
Synonyms: Vardenafil Hydrochloride;Valdenafil HCl;Vardenafil Hydrochloride Salt;1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine dihydrochloride;
1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine
CAS:224785-91-5
MF: C23H33ClN6O4S
MW:525.06
Chemical Properties:White to off-white cyrstalline solid
Usage:A selective phsphodiesterase type 5 (PDE5) inhibitor.
Packing:1kg/Tin
Applicaiton of Vardenafil:

Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Further, Vardenafil causing lengthening of the QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as amiodarone).

COA of Vardenafil:

Test Items	Specification	Test Results
Description	White or almost white crystalline powder	White crystalline powder
Melting Point	284.0~285.0°C	284.0ºC
TLC	Only one spot	Only one spot
Loss on drying	≤1.0%	0.5%
Heavy metals	≤20ppm	15ppm
Assay	≥99.5%	99.91%

Vardenafil:The average working time is 15 to 30 minutes,the side effects are small.However, due to individual differences, there are still less than 2% of people will feel a slight headache. Soluble in water and ethanol.

Vardenafil hydrochloride Recommended dose:
Suggested starting usage is 10mg ,need use it 25-60minutes before having sex.
In clinical trials, having sex to take 4 to 5 hours before, still display effect.Medication frequency limit for once a day. ,not affected by eating.Need to sexual stimulation effect to make this product effect

Dose range:The dosage is from 5 to 20 mg/day, according to the constitution of different dosage. Adjust the dosage according to the different physical


Side effects:
1.Liver damage,
child-pugh A :Don need to adjust the dosage
child-pugh B:As Vardenafils clearance to reduce, advice start from 10mg,then according to the tolerability and efficacy gradually increased to 10 mg.
child-pugh C:Research has not yet been.Not Recommended.
2. Renal damage
Patients of mild, moderate or severe renal impairment don need to adjust the doseage.
Vardenafil of dialysis patients pharmacokinetic research has not yet been performed.
Not Recommended.

Drug combination:
As sometimes use Vardenafil and Alpha blockers together may result in symptomatic hypotension,so
drug combination just only applicable to patients accept alpha blockers treatment in stable condition.They start dose is 5mg.

Attention:
As having sex with a certain degree of heart risk, then dcotor should first consider his heart condition before taking any treatment on patients with erectile dysfunction.

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